|
Symbol Name ID |
Vdr
vitamin D (1,25-dihydroxyvitamin D3) receptor MGI:103076 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgM level |
Allergic rhinitis |
Conjunctivitis |
Splenomegaly |
Celiac disease |
Gastrointestinal inflammation |
Hepatitis |
Subacute progressive viral hepatitis |
Iridocyclitis |
Epididymitis |
Eczematoid dermatitis |
Atopic dermatitis |
Erythema nodosum |
Recurrent skin infections |
Autoimmunity |
Anti-citrullinated protein antibody positivity |
Antimitochondrial antibody positivity |
Antinuclear antibody positivity |
Rheumatoid factor positive |
Asthma |
Recurrent fungal infections |
Onychomycosis |
| Disease(s) Associated with VDR | |||||||||||||||||||||||
| asthma | |||||||||||||||||||||||
| atopic dermatitis | |||||||||||||||||||||||
| Behcet's disease | |||||||||||||||||||||||
| hepatocellular carcinoma | |||||||||||||||||||||||
| primary biliary cholangitis | |||||||||||||||||||||||
| rheumatoid arthritis |
| Mouse Phenotypes | immune system phenotype |
abnormal dendritic cell differentiation |
abnormal osteoclast differentiation |
abnormal macrophage chemotaxis |
decreased splenocyte proliferation |
increased susceptibility to induced colitis |
intestinal inflammation |
increased thymus weight |
thymus hyperplasia |
ear inflammation |
abnormal T cell number |
decreased regulatory T cell number |
decreased osteoclast cell number |
abnormal macrophage physiology |
abnormal interleukin level |
abnormal tumor necrosis factor level |
abnormal chemokine secretion |
abnormal interleukin-1 secretion |
decreased interleukin-6 secretion |
decreased susceptibility to autoimmune diabetes |
increased susceptibility to autoimmune diabetes |
dermatitis |
decreased susceptibility to parasitic infection |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||
| Vdrtm1Mbd/Vdrtm1Mbd | * | |||||||||||||||||||||||
| Vdrtm1Rge/Vdrtm1Rge | ||||||||||||||||||||||||
| Vdrtm1Ska/Vdrtm1Ska | ||||||||||||||||||||||||
| Vdrtm2Ska/Vdrtm2Ska | ||||||||||||||||||||||||
| Vdrtm1Gcm/Vdrtm1Gcm Tg(Col2a1-cre)1Bhr/? (conditional) |
||||||||||||||||||||||||
| Tg(Col1a1-cre)1Kry/0 Vdrtm2Ska/Vdrtm2Ska (conditional) |
||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 05/14/2024 MGI 6.23 |
|
|
|
||
Analysis Tools